![]() The amount of activity that might aggravate the illness is difficult for a person to predict, and the decline often presents 12 to 48 hours after the activity. Worsening of symptoms after physical or mental activity that would not have caused a problem before the illness.This drop in activity level occurs along with fatigue and must last six months or longer. Greatly lowered ability to do activities that were usual before the illness.The United States Centers for Disease Control and Prevention (CDC) recommends these criteria for diagnosis: Results of studies of proposed causes and treatments are often poor or contradictory. Various physicians, researchers, and patient advocates promote different names and diagnostic criteria. There is controversy over many aspects of the disorder. : 183 CFS significantly reduces health, happiness, productivity, and can also cause socio-emotional disruptions such as loneliness and alienation. : 182 Chronic fatigue syndrome is a major cause of school absence. Other studies suggest that about 0.5% of children have CFS, and that it is more common in adolescents than in younger children. It most commonly affects adults between ages 40 and 60 years it can occur at other ages, including childhood. CFS occurs 1.5 to 2 times as often in women as in men. It has been estimated that 836,000 to 2.5 million Americans and 250,000 to 1,250,000 people in the United Kingdom have CFS. Limited evidence suggests that counseling, personalized activity management, and the use of rintatolimod help improve some patients' functional abilities.Ībout 1% of primary-care patients have CFS estimates of incidence vary widely because various epidemiological studies have used dissimilar definitions. The CDC recommends pacing (personal activity management) to keep mental and physical activity from making symptoms worse. No therapies or medications are approved to treat the cause of the illness treatment is aimed at alleviation of symptoms. Persons with CFS may recover or improve over time, but some will become severely affected and disabled for an extended period. Proposed mechanisms include biological, genetic, epigenetic, infectious, and physical or psychological stress affecting the biochemistry of the body. Diagnosis is based on the person's symptoms because no confirmed diagnostic test is available. The often incapacitating fatigue in CFS is different from that caused by normal strenuous ongoing exertion, is not significantly relieved by rest, and is not due to a previous medical condition. Frequently and variably, other common symptoms occur involving numerous body systems, and chronic pain is very common. : 7 The Center for Disease Control and Prevention’s (CDC) diagnostic criteria also require at least one of the following: (1) Orthostatic intolerance (difficulty sitting and standing upright) or (2) impaired memory or attention. Distinguishing core symptoms are lengthy exacerbations or flare-ups of the illness following ordinary minor physical or mental activity, known as post-exertional malaise (PEM) greatly diminished capacity to accomplish tasks that were routine before the illness and sleep disturbances. The root cause(s) of the disease are unknown and the mechanisms are not fully understood. Worsening of symptoms with activity, long-term fatigue, others įemale sex, virus and bacterial infections, blood relatives with the illness, major injury, bodily response to severe stress and others : 1–2Ĭhronic fatigue syndrome ( CFS), also called myalgic encephalomyelitis ( ME) or ME/CFS, is a complex, debilitating, long-term medical condition. Rheumatology, rehabilitation medicine, endocrinology, Infectious disease, neurology, immunology, internal medicine, paediatrics, other specialists in ME/CFS Myalgic encephalomyelitis/ chronic fatigue syndrome (ME/CFS), myalgic encephalomyelitis (ME), post-viral fatigue syndrome (PVFS), chronic fatigue immune dysfunction syndrome (CFIDS), systemic exertion intolerance disease (SEID), others : 20Ĭhart of the symptoms of CFS according to various definitions Medical condition Chronic fatigue syndrome
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